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The mast cells rupture – and in the process, release biochemical substances including histamine.
Mild allergy symptoms include itchy, watery eyes, a runny nose, scratchy throat and a rash.
They don't relieve other allergy symptoms such as itching and sneezing.
Immunomodulators: These are topical medications used to treat skin allergies.
Anticholinergic nasal sprays reduce discharge from the nose, but though they do not relieve a stuffy nose.
Interactions with other drugs are more common with first-generation antihistamines compared with second-generation antihistamines.
Second generation antihistamines were developed in the 1980s and are much less sedating than first-generation antihistamines.
In addition to oral dosage forms, antihistamines come as creams, lotions, nasal sprays, and eye drops; the latter to relieve symptoms associated with allergic conjunctivitis.
Other types of allergy drugs include: Corticosteroids: These come as nasal sprays, topical creams and ointments, tablets, injectables and eye preparations. Mast cell stabilizers: These can help prevent allergic reactions from happening when taken regularly.